Nitric oxide synthase in motor neurons after axotomy.
نویسندگان
چکیده
منابع مشابه
Depolarization of mitochondria in neurons promotes activation of nitric oxide synthase and generation of nitric oxide.
The diverse signaling events following mitochondrial depolarization in neurons are not clear. We examined for the first time the effects of mitochondrial depolarization on mitochondrial function, intracellular calcium, neuronal nitric oxide synthase (nNOS) activation, and nitric oxide (NO) production in cultured neurons and perivascular nerves. Cultured rat primary cortical neurons were studied...
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Inhibitory neurons are critical for regulating effective transfer of sensory information and network stability. The precision of inhibitory function likely derives from the existence of a variety of interneuron subtypes. Their specification is largely dependent on the locale of origin of interneuron progenitors. Neocortical and hippocampal inhibitory neurons originate the subpallium, namely in ...
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Nitric oxide (NO) regulates several cellular functions via reversible regulation of mitochondrial respiration. Nitric oxide also reacts with mitochondrial superoxide anion to produce the potent oxidative species peroxynitrite that irreversibly hinders mitochondrial activities. Recent findings demonstrating that mitochondria produce NO via mitochondrial NO synthase (mtNOS) has intrigued several ...
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The effect of hyperoxia on nitric oxide (NO) production in intact animals is unknown. We described the effects of hyperoxia on inducible nitric oxide synthase (iNOS) expression and NO production in the lungs of rats exposed to high concentrations of oxygen. Animals were placed in sealed Plexiglas chambers and were exposed to either 85% oxygen (hyperoxic group) or 21% oxygen (negative control gr...
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We read with great interest the paper by Comini et al. which demonstrates the induction of inducible nitric oxide synthase (iNOS) expression in circulating monocytes of patients with chronic heart failure. As we believe this paper reports upon a very important aspect of current research, we would like to comment on two aspects which we think are of special interest. Firstly, the activation of t...
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ژورنال
عنوان ژورنال: Journal of Histochemistry & Cytochemistry
سال: 1994
ISSN: 0022-1554,1551-5044
DOI: 10.1177/42.4.7510317